null

SMILES: CNC(=O)Cn1cc(C2CC2)c(Oc2ccc(cc2)C#N)c1C1CC1

InChI Key: InChIKey=AALHNBNOUAEYHF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50318934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50318934 (2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...) Show SMILES CNC(=O)Cn1cc(C2CC2)c(Oc2ccc(cc2)C#N)c1C1CC1 Show InChI InChI=1S/C20H21N3O2/c1-22-18(24)12-23-11-17(14-4-5-14)20(19(23)15-6-7-15)25-16-8-2-13(10-21)3-9-16/h2-3,8-9,11,14-15H,4-7,12H2,1H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50318934 (2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...) Show SMILES CNC(=O)Cn1cc(C2CC2)c(Oc2ccc(cc2)C#N)c1C1CC1 Show InChI InChI=1S/C20H21N3O2/c1-22-18(24)12-23-11-17(14-4-5-14)20(19(23)15-6-7-15)25-16-8-2-13(10-21)3-9-16/h2-3,8-9,11,14-15H,4-7,12H2,1H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50318934 (2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...) Show SMILES CNC(=O)Cn1cc(C2CC2)c(Oc2ccc(cc2)C#N)c1C1CC1 Show InChI InChI=1S/C20H21N3O2/c1-22-18(24)12-23-11-17(14-4-5-14)20(19(23)15-6-7-15)25-16-8-2-13(10-21)3-9-16/h2-3,8-9,11,14-15H,4-7,12H2,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Inhibition of androgen receptor				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50318934 (2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...) Show SMILES CNC(=O)Cn1cc(C2CC2)c(Oc2ccc(cc2)C#N)c1C1CC1 Show InChI InChI=1S/C20H21N3O2/c1-22-18(24)12-23-11-17(14-4-5-14)20(19(23)15-6-7-15)25-16-8-2-13(10-21)3-9-16/h2-3,8-9,11,14-15H,4-7,12H2,1H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Inhibition of glucocorticoid receptor				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50318934 (2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...) Show SMILES CNC(=O)Cn1cc(C2CC2)c(Oc2ccc(cc2)C#N)c1C1CC1 Show InChI InChI=1S/C20H21N3O2/c1-22-18(24)12-23-11-17(14-4-5-14)20(19(23)15-6-7-15)25-16-8-2-13(10-21)3-9-16/h2-3,8-9,11,14-15H,4-7,12H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Inhibition of estrogen receptor				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50318934 (2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...) Show SMILES CNC(=O)Cn1cc(C2CC2)c(Oc2ccc(cc2)C#N)c1C1CC1 Show InChI InChI=1S/C20H21N3O2/c1-22-18(24)12-23-11-17(14-4-5-14)20(19(23)15-6-7-15)25-16-8-2-13(10-21)3-9-16/h2-3,8-9,11,14-15H,4-7,12H2,1H3,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Inhibition of mineralocorticoid receptor				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair