null

SMILES: CCc1cn(CCO)c(CC)c1Oc1ccc(cc1)C#N

InChI Key: InChIKey=BZNHAHNOAXOEDO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50318943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50318943 (4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...) Show SMILES CCc1cn(CCO)c(CC)c1Oc1ccc(cc1)C#N Show InChI InChI=1S/C17H20N2O2/c1-3-14-12-19(9-10-20)16(4-2)17(14)21-15-7-5-13(11-18)6-8-15/h5-8,12,20H,3-4,9-10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50318943 (4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...) Show SMILES CCc1cn(CCO)c(CC)c1Oc1ccc(cc1)C#N Show InChI InChI=1S/C17H20N2O2/c1-3-14-12-19(9-10-20)16(4-2)17(14)21-15-7-5-13(11-18)6-8-15/h5-8,12,20H,3-4,9-10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Inhibition of androgen receptor				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50318943 (4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...) Show SMILES CCc1cn(CCO)c(CC)c1Oc1ccc(cc1)C#N Show InChI InChI=1S/C17H20N2O2/c1-3-14-12-19(9-10-20)16(4-2)17(14)21-15-7-5-13(11-18)6-8-15/h5-8,12,20H,3-4,9-10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Inhibition of mineralocorticoid receptor				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50318943 (4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...) Show SMILES CCc1cn(CCO)c(CC)c1Oc1ccc(cc1)C#N Show InChI InChI=1S/C17H20N2O2/c1-3-14-12-19(9-10-20)16(4-2)17(14)21-15-7-5-13(11-18)6-8-15/h5-8,12,20H,3-4,9-10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Inhibition of glucocorticoid receptor				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50318943 (4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...) Show SMILES CCc1cn(CCO)c(CC)c1Oc1ccc(cc1)C#N Show InChI InChI=1S/C17H20N2O2/c1-3-14-12-19(9-10-20)16(4-2)17(14)21-15-7-5-13(11-18)6-8-15/h5-8,12,20H,3-4,9-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer PharmaTherapeutics Division Curated by ChEMBL					Assay Description Inhibition of estrogen receptor				Bioorg Med Chem Lett 20: 3384-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.018 BindingDB Entry DOI: 10.7270/Q2NK3F6K
					More data for this Ligand-Target Pair