BDBM50319104 5-(6-fluoropyridin-3-yl)-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid::CHEMBL1083450

SMILES: OC(=O)C1=C(CCC(C1)c1ccc(F)nc1)NC(=O)CCc1ccc2cc(O)ccc2c1

InChI Key: InChIKey=HASLRSOJAVCZLP-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50319104 (5-(6-fluoropyridin-3-yl)-2-(3-(6-hydroxynaphthalen...) Show SMILES OC(=O)C1=C(CCC(C1)c1ccc(F)nc1)NC(=O)CCc1ccc2cc(O)ccc2c1 |t:3| Show InChI InChI=1S/C25H23FN2O4/c26-23-9-6-19(14-27-23)18-5-8-22(21(13-18)25(31)32)28-24(30)10-2-15-1-3-17-12-20(29)7-4-16(17)11-15/h1,3-4,6-7,9,11-12,14,18,29H,2,5,8,10,13H2,(H,28,30)(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at human niacin receptor expressed in CHO-KI cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 20: 3426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.04.001 BindingDB Entry DOI: 10.7270/Q2W0963X
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50319104 (5-(6-fluoropyridin-3-yl)-2-(3-(6-hydroxynaphthalen...) Show SMILES OC(=O)C1=C(CCC(C1)c1ccc(F)nc1)NC(=O)CCc1ccc2cc(O)ccc2c1 |t:3| Show InChI InChI=1S/C25H23FN2O4/c26-23-9-6-19(14-27-23)18-5-8-22(21(13-18)25(31)32)28-24(30)10-2-15-1-3-17-12-20(29)7-4-16(17)11-15/h1,3-4,6-7,9,11-12,14,18,29H,2,5,8,10,13H2,(H,28,30)(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CHO-KI cells				Bioorg Med Chem Lett 20: 3426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.04.001 BindingDB Entry DOI: 10.7270/Q2W0963X
					More data for this Ligand-Target Pair