BDBM50320075 1-Benzyl-2-heptyl-1H-imidazo[4,5-c]quinolin-4-amine::CHEMBL1086372

SMILES: CCCCCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1

InChI Key: InChIKey=HTAZDMCWIPXKAA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50320075 (1-Benzyl-2-heptyl-1H-imidazo[4,5-c]quinolin-4-amin...) Show SMILES CCCCCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 Show InChI InChI=1S/C24H28N4/c1-2-3-4-5-9-16-21-27-22-23(28(21)17-18-12-7-6-8-13-18)19-14-10-11-15-20(19)26-24(22)25/h6-8,10-15H,2-5,9,16-17H2,1H3,(H2,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	822	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in NFkappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by rep...				J Med Chem 53: 4450-65 (2010) Article DOI: 10.1021/jm100358c BindingDB Entry DOI: 10.7270/Q2Q52PS6
					More data for this Ligand-Target Pair