null
SMILES: CN1[C@@H](CCc2ccnc3ccccc23)CCC[C@H]1CCc1ccnc2ccccc12
InChI Key: InChIKey=QQIWJQRMRXZSJG-PSWAGMNNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50320380 (CHEMBL1083434 | cis-4,4'-(2,2'-(-1-methylpiperidin...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky Curated by ChEMBL | Assay Description Inhibition of VMAT2-mediated [3H]dopamine uptake in rat synaptic vesicle membranes | Bioorg Med Chem Lett 20: 3584-7 (2010) Article DOI: 10.1016/j.bmcl.2010.04.117 BindingDB Entry DOI: 10.7270/Q2N879Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50320380 (CHEMBL1083434 | cis-4,4'-(2,2'-(-1-methylpiperidin...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky Curated by ChEMBL | Assay Description Displacement of [3H]DTBZ from VMAT2 in rat synaptic vesicle membranes after 30 mins by liquid scintillation counting | Bioorg Med Chem Lett 20: 3584-7 (2010) Article DOI: 10.1016/j.bmcl.2010.04.117 BindingDB Entry DOI: 10.7270/Q2N879Z6 | |||||||||||
More data for this Ligand-Target Pair |