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SMILES: Nc1ccccc1NC(=O)c1ccc(CNCc2cc3ccccc3s2)cc1

InChI Key: InChIKey=ZDGYJGUGZZLURY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320755   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50320755
PNG
(CHEMBL1165102 | N-(2-aminophenyl)-4-((benzo[b]thio...)
Show SMILES Nc1ccccc1NC(=O)c1ccc(CNCc2cc3ccccc3s2)cc1
Show InChI InChI=1S/C23H21N3OS/c24-20-6-2-3-7-21(20)26-23(27)17-11-9-16(10-12-17)14-25-15-19-13-18-5-1-4-8-22(18)28-19/h1-13,25H,14-15,24H2,(H,26,27)
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MMDB

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Similars
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Kansai University

Curated by ChEMBL


Assay Description
Inhibition of HDAC1

Bioorg Med Chem 18: 3925-33 (2010)


Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H
More data for this
Ligand-Target Pair