BDBM50320783 (Z)-5-(4-phenoxybenzylidene)-3-(3,3,3-trifluoro-2,2-dihydroxypropyl)thiazolidine-2,4-dione::CHEMBL1165383

SMILES: OC(O)(CN1C(=O)S\C(=C/c2ccc(Oc3ccccc3)cc2)C1=O)C(F)(F)F

InChI Key: InChIKey=BNSRUJZMCZNECP-GDNBJRDFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (ALR2) (Bos taurus (Cattle))	BDBM50320783 ((Z)-5-(4-phenoxybenzylidene)-3-(3,3,3-trifluoro-2,...) Show SMILES OC(O)(CN1C(=O)S\C(=C/c2ccc(Oc3ccccc3)cc2)C1=O)C(F)(F)F Show InChI InChI=1S/C19H14F3NO5S/c20-19(21,22)18(26,27)11-23-16(24)15(29-17(23)25)10-12-6-8-14(9-7-12)28-13-4-2-1-3-5-13/h1-10,26-27H,11H2/b15-10-	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of bovine lens aldose reductase				Bioorg Med Chem 18: 4049-55 (2010) Article DOI: 10.1016/j.bmc.2010.04.016 BindingDB Entry DOI: 10.7270/Q2RN38VN
					More data for this Ligand-Target Pair