BDBM50322605 CHEMBL1173337::Diisopropyl 2-(sulfanylmethyl)phenylphosphonate::bis(1-methylethyl) [2-(sulfanylmethyl)phenyl]phosphonate
SMILES: CC(C)OP(=O)(OC(C)C)c1ccccc1CS
InChI Key: InChIKey=JFZVPWMZPZJUTE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase (Aeromonas hydrophila) | BDBM50322605 (CHEMBL1173337 | Diisopropyl 2-(sulfanylmethyl)phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge Curated by ChEMBL | Assay Description Inhibition of Aeromonas hydrophila cphA | J Med Chem 53: 4862-76 (2010) Article DOI: 10.1021/jm100213c BindingDB Entry DOI: 10.7270/Q2057G34 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-lactamase L1 (Stenotrophomonas maltophilia) | BDBM50322605 (CHEMBL1173337 | Diisopropyl 2-(sulfanylmethyl)phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge Curated by ChEMBL | Assay Description Inhibition of Stenotrophomonas maltophilia beta lactamase L1 in absence of Zn+ chelator | J Med Chem 53: 4862-76 (2010) Article DOI: 10.1021/jm100213c BindingDB Entry DOI: 10.7270/Q2057G34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase L1 (Stenotrophomonas maltophilia) | BDBM50322605 (CHEMBL1173337 | Diisopropyl 2-(sulfanylmethyl)phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge Curated by ChEMBL | Assay Description Inhibition of Stenotrophomonas maltophilia beta lactamase L1 in presence of Zn+ chelator | J Med Chem 53: 4862-76 (2010) Article DOI: 10.1021/jm100213c BindingDB Entry DOI: 10.7270/Q2057G34 | |||||||||||
More data for this Ligand-Target Pair |