BindingDB logo
myBDB logout

null

SMILES: OC(=O)c1c(NCc2ccccc2)ncnc1SCc1ccccc1

InChI Key: InChIKey=UOQZGCFZUHJMFP-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322675   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50322675
PNG
(4-(Benzylamino)-6-(benzylthio)pyrimidine-5-carboxy...)
Show SMILES OC(=O)c1c(NCc2ccccc2)ncnc1SCc1ccccc1
Show InChI InChI=1S/C19H17N3O2S/c23-19(24)16-17(20-11-14-7-3-1-4-8-14)21-13-22-18(16)25-12-15-9-5-2-6-10-15/h1-10,13H,11-12H2,(H,23,24)(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Kyorin Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Partial agonist activity at human PPARgamma-LBD expressed in CHO-K1 cells co-transfected with GAL4 assessed as luciferase activity by transactivation...

J Med Chem 53: 5012-24 (2010)


Article DOI: 10.1021/jm100443s
BindingDB Entry DOI: 10.7270/Q24J0G3H
More data for this
Ligand-Target Pair