BDBM50322793 4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol::CHEMBL1172779

SMILES: Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1

InChI Key: InChIKey=KOYRCBKCALKGKO-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50322793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP17 expressed in Escherichia coli				J Med Chem 53: 5749-58 (2010) Article DOI: 10.1021/jm100317b BindingDB Entry DOI: 10.7270/Q24B31J1
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster fibroblast				J Med Chem 53: 5749-58 (2010) Article DOI: 10.1021/jm100317b BindingDB Entry DOI: 10.7270/Q24B31J1
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	948	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster fibroblast				J Med Chem 53: 5749-58 (2010) Article DOI: 10.1021/jm100317b BindingDB Entry DOI: 10.7270/Q24B31J1
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental CYP19				J Med Chem 53: 5749-58 (2010) Article DOI: 10.1021/jm100317b BindingDB Entry DOI: 10.7270/Q24B31J1
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of CYP3A4 expressed in baculovirus infected insect microsomes				J Med Chem 53: 5049-53 (2010) Article DOI: 10.1021/jm100400a BindingDB Entry DOI: 10.7270/Q2W37X9K
					More data for this Ligand-Target Pair
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductase				J Med Chem 53: 5049-53 (2010) Article DOI: 10.1021/jm100400a BindingDB Entry DOI: 10.7270/Q2W37X9K
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79MZh cells				J Med Chem 53: 5049-53 (2010) Article DOI: 10.1021/jm100400a BindingDB Entry DOI: 10.7270/Q2W37X9K
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	948	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79MZh cells				J Med Chem 53: 5049-53 (2010) Article DOI: 10.1021/jm100400a BindingDB Entry DOI: 10.7270/Q2W37X9K
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of CYP19 in human placental microsomes				J Med Chem 53: 5049-53 (2010) Article DOI: 10.1021/jm100400a BindingDB Entry DOI: 10.7270/Q2W37X9K
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50322793 (4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...) Show SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1 Show InChI InChI=1S/C18H15NO2/c20-17-6-5-16(12-18(17)21)15-3-1-13(2-4-15)11-14-7-9-19-10-8-14/h1-10,12,20-21H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsome				J Med Chem 53: 5749-58 (2010) Article DOI: 10.1021/jm100317b BindingDB Entry DOI: 10.7270/Q24B31J1
					More data for this Ligand-Target Pair