BDBM50323277 CHEMBL1209551::N-(3-tert-butylphenyl)-3-cyano-5-fluorobenzamide

SMILES: CC(C)(C)c1cccc(NC(=O)c2cc(F)cc(c2)C#N)c1

InChI Key: InChIKey=PVVDTFDEBDJDJV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323277 (CHEMBL1209551 | N-(3-tert-butylphenyl)-3-cyano-5-f...) Show SMILES CC(C)(C)c1cccc(NC(=O)c2cc(F)cc(c2)C#N)c1 Show InChI InChI=1S/C18H17FN2O/c1-18(2,3)14-5-4-6-16(10-14)21-17(22)13-7-12(11-20)8-15(19)9-13/h4-10H,1-3H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium mobilization				Bioorg Med Chem Lett 20: 4390-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.064 BindingDB Entry DOI: 10.7270/Q2V9888D
					More data for this Ligand-Target Pair