BDBM50323313 3-cyano-5-fluoro-N-(pyridin-3-yl)benzamide::CHEMBL1209205

SMILES: Fc1cc(cc(c1)C(=O)Nc1cccnc1)C#N

InChI Key: InChIKey=YQZDHDCVBIQFEB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50323313 (3-cyano-5-fluoro-N-(pyridin-3-yl)benzamide | CHEMB...) Show SMILES Fc1cc(cc(c1)C(=O)Nc1cccnc1)C#N Show InChI InChI=1S/C13H8FN3O/c14-11-5-9(7-15)4-10(6-11)13(18)17-12-2-1-3-16-8-12/h1-6,8H,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium mobilization				Bioorg Med Chem Lett 20: 4390-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.064 BindingDB Entry DOI: 10.7270/Q2V9888D
					More data for this Ligand-Target Pair