BDBM50323903 (E)-4-(3-(4-(4-(4-Chlorophenoxy)butoxy)phenyl)acryloyl)-3-(cyanomethoxy)benzoic acid::CHEMBL1213917
SMILES: OC(=O)c1ccc(C(=O)\C=C\c2ccc(OCCCCOc3ccc(Cl)cc3)cc2)c(OCC#N)c1
InChI Key: InChIKey=ZTHMJAISOYJLLS-LHHJGKSTSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cysteinyl leukotriene receptor (Homo sapiens (Human)) | BDBM50323903 ((E)-4-(3-(4-(4-(4-Chlorophenoxy)butoxy)phenyl)acry...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 480 | n/a | n/a | n/a | n/a |
Zhejiang University Curated by ChEMBL | Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... | Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0 | |||||||||||
More data for this Ligand-Target Pair |