null

SMILES: COc1cc(OC)c(-c2cc(n[nH]2)-c2ccc(cc2Cl)[N+]([O-])=O)c(O)c1C1CCN(C)C1CO

InChI Key: InChIKey=WZUZZJOQIBQWOW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50324035 (2-[5-(2-Chloro-4-nitro-phenyl)-1H-pyrazol-3-yl]-6-...) Show SMILES COc1cc(OC)c(-c2cc(n[nH]2)-c2ccc(cc2Cl)[N+]([O-])=O)c(O)c1C1CCN(C)C1CO Show InChI InChI=1S/C23H25ClN4O6/c1-27-7-6-14(18(27)11-29)21-19(33-2)10-20(34-3)22(23(21)30)17-9-16(25-26-17)13-5-4-12(28(31)32)8-15(13)24/h4-5,8-10,14,18,29-30H,6-7,11H2,1-3H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solapur University Curated by ChEMBL					Assay Description Inhibition of mashroom tyrosinase				Bioorg Med Chem 18: 6149-55 (2010) Article DOI: 10.1016/j.bmc.2010.06.046 BindingDB Entry DOI: 10.7270/Q2GQ6XXR
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50324035 (2-[5-(2-Chloro-4-nitro-phenyl)-1H-pyrazol-3-yl]-6-...) Show SMILES COc1cc(OC)c(-c2cc(n[nH]2)-c2ccc(cc2Cl)[N+]([O-])=O)c(O)c1C1CCN(C)C1CO Show InChI InChI=1S/C23H25ClN4O6/c1-27-7-6-14(18(27)11-29)21-19(33-2)10-20(34-3)22(23(21)30)17-9-16(25-26-17)13-5-4-12(28(31)32)8-15(13)24/h4-5,8-10,14,18,29-30H,6-7,11H2,1-3H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solapur University Curated by ChEMBL					Assay Description Inhibition of mashroom tyrosinase assessed as oxidation of L-DOPA				Bioorg Med Chem 18: 6149-55 (2010) Article DOI: 10.1016/j.bmc.2010.06.046 BindingDB Entry DOI: 10.7270/Q2GQ6XXR
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50324035 (2-[5-(2-Chloro-4-nitro-phenyl)-1H-pyrazol-3-yl]-6-...) Show SMILES COc1cc(OC)c(-c2cc(n[nH]2)-c2ccc(cc2Cl)[N+]([O-])=O)c(O)c1C1CCN(C)C1CO Show InChI InChI=1S/C23H25ClN4O6/c1-27-7-6-14(18(27)11-29)21-19(33-2)10-20(34-3)22(23(21)30)17-9-16(25-26-17)13-5-4-12(28(31)32)8-15(13)24/h4-5,8-10,14,18,29-30H,6-7,11H2,1-3H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Solapur University Curated by ChEMBL					Assay Description Inhibition of mashroom tyrosinase assessed as oxidation of L-DOPA				Bioorg Med Chem 18: 6149-55 (2010) Article DOI: 10.1016/j.bmc.2010.06.046 BindingDB Entry DOI: 10.7270/Q2GQ6XXR
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50324035 (2-[5-(2-Chloro-4-nitro-phenyl)-1H-pyrazol-3-yl]-6-...) Show SMILES COc1cc(OC)c(-c2cc(n[nH]2)-c2ccc(cc2Cl)[N+]([O-])=O)c(O)c1C1CCN(C)C1CO Show InChI InChI=1S/C23H25ClN4O6/c1-27-7-6-14(18(27)11-29)21-19(33-2)10-20(34-3)22(23(21)30)17-9-16(25-26-17)13-5-4-12(28(31)32)8-15(13)24/h4-5,8-10,14,18,29-30H,6-7,11H2,1-3H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Solapur University Curated by ChEMBL					Assay Description Inhibition of mashroom tyrosinase				Bioorg Med Chem 18: 6149-55 (2010) Article DOI: 10.1016/j.bmc.2010.06.046 BindingDB Entry DOI: 10.7270/Q2GQ6XXR
					More data for this Ligand-Target Pair