BDBM50324072 2-Chloro-4-phenyl-6-(piperidin-1-yl)pyridine-3,5-dicarbonitrile::CHEMBL1215178

SMILES: Clc1nc(N2CCCCC2)c(C#N)c(-c2ccccc2)c1C#N

InChI Key: InChIKey=NTRONXYCBZGXQE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Butyrylcholinesterase (BChE) (Equus caballus (Horse))	BDBM50324072 (2-Chloro-4-phenyl-6-(piperidin-1-yl)pyridine-3,5-d...) Show SMILES Clc1nc(N2CCCCC2)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C18H15ClN4/c19-17-14(11-20)16(13-7-3-1-4-8-13)15(12-21)18(22-17)23-9-5-2-6-10-23/h1,3-4,7-8H,2,5-6,9-10H2	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Radicales Libres y Química Computacional (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of equine serum BuChE after 10 mins by Ellman's method				Bioorg Med Chem 18: 5861-72 (2010) Article DOI: 10.1016/j.bmc.2010.06.095 BindingDB Entry DOI: 10.7270/Q23J3D5D
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50324072 (2-Chloro-4-phenyl-6-(piperidin-1-yl)pyridine-3,5-d...) Show SMILES Clc1nc(N2CCCCC2)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C18H15ClN4/c19-17-14(11-20)16(13-7-3-1-4-8-13)15(12-21)18(22-17)23-9-5-2-6-10-23/h1,3-4,7-8H,2,5-6,9-10H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Radicales Libres y Química Computacional (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE after 10 mins by Ellman's method				Bioorg Med Chem 18: 5861-72 (2010) Article DOI: 10.1016/j.bmc.2010.06.095 BindingDB Entry DOI: 10.7270/Q23J3D5D
					More data for this Ligand-Target Pair