BDBM50324761 (3R,4R)-propyl 3-(4-chlorophenylcarbamoyl)-4-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenylcarbamoyl)pyrrolidine-1-carboxylate::CHEMBL1221725

SMILES: CCCOC(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=XOODLPVVNFYOQH-SFTDATJTSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324761 ((3R,4R)-propyl 3-(4-chlorophenylcarbamoyl)-4-(2-fl...) Show SMILES CCCOC(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)C(=O)Nc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H26ClFN4O5/c1-2-13-38-27(37)32-15-20(25(35)30-18-8-6-17(28)7-9-18)21(16-32)26(36)31-23-11-10-19(14-22(23)29)33-12-4-3-5-24(33)34/h3-12,14,20-21H,2,13,15-16H2,1H3,(H,30,35)(H,31,36)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50324761 ((3R,4R)-propyl 3-(4-chlorophenylcarbamoyl)-4-(2-fl...) Show SMILES CCCOC(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)C(=O)Nc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H26ClFN4O5/c1-2-13-38-27(37)32-15-20(25(35)30-18-8-6-17(28)7-9-18)21(16-32)26(36)31-23-11-10-19(14-22(23)29)33-12-4-3-5-24(33)34/h3-12,14,20-21H,2,13,15-16H2,1H3,(H,30,35)(H,31,36)/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair