BDBM50325828 CHEMBL1224609::N-(2-(3-(2-(cyclopropylmethylamino)-2-oxoethyl)-4-oxo-2-phenyl-3,4-dihydroquinazolin-6-yloxy)ethyl)-3-(4-hydroxyphenyl)propanamide

SMILES: Oc1ccc(CCC(=O)NCCOc2ccc3nc(-c4ccccc4)n(CC(=O)NCC4CC4)c(=O)c3c2)cc1

InChI Key: InChIKey=IKAYYYUNFUAKCG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1b receptor (Homo sapiens (Human))	BDBM50325828 (CHEMBL1224609 | N-(2-(3-(2-(cyclopropylmethylamino...) Show SMILES Oc1ccc(CCC(=O)NCCOc2ccc3nc(-c4ccccc4)n(CC(=O)NCC4CC4)c(=O)c3c2)cc1 Show InChI InChI=1S/C31H32N4O5/c36-24-11-8-21(9-12-24)10-15-28(37)32-16-17-40-25-13-14-27-26(18-25)31(39)35(20-29(38)33-19-22-6-7-22)30(34-27)23-4-2-1-3-5-23/h1-5,8-9,11-14,18,22,36H,6-7,10,15-17,19-20H2,(H,32,37)(H,33,38)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]AVP from human vasopresin3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 5394-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.118 BindingDB Entry DOI: 10.7270/Q2222TZ5
					More data for this Ligand-Target Pair