BDBM50326381 2S)-1-({(2S,4S)-4-[2-(6,7-Dihydrothieno[3,2-c]pyridin-5(4H)-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile::CHEMBL1242993

SMILES: O=C(C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N)N1CCc2ccsc2C1

InChI Key: InChIKey=QTZMSDAPQLNSRC-KKUMJFAQSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast activation protein alpha (Homo sapiens (Human))	BDBM50326381 (2S)-1-({(2S,4S)-4-[2-(6,7-Dihydrothieno[3,2-c]pyri...) Show SMILES O=C(C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N)N1CCc2ccsc2C1 |r| Show InChI InChI=1S/C19H22N4O3S/c20-10-14-2-1-5-23(14)19(26)15-8-13(18(25)21-15)9-17(24)22-6-3-12-4-7-27-16(12)11-22/h4,7,13-15H,1-3,5-6,8-9,11H2,(H,21,25)/t13-,14-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant FAP expressed in Hi5 insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50326381 (2S)-1-({(2S,4S)-4-[2-(6,7-Dihydrothieno[3,2-c]pyri...) Show SMILES O=C(C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N)N1CCc2ccsc2C1 |r| Show InChI InChI=1S/C19H22N4O3S/c20-10-14-2-1-5-23(14)19(26)15-8-13(18(25)21-15)9-17(24)22-6-3-12-4-7-27-16(12)11-22/h4,7,13-15H,1-3,5-6,8-9,11H2,(H,21,25)/t13-,14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP8 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50326381 (2S)-1-({(2S,4S)-4-[2-(6,7-Dihydrothieno[3,2-c]pyri...) Show SMILES O=C(C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N)N1CCc2ccsc2C1 |r| Show InChI InChI=1S/C19H22N4O3S/c20-10-14-2-1-5-23(14)19(26)15-8-13(18(25)21-15)9-17(24)22-6-3-12-4-7-27-16(12)11-22/h4,7,13-15H,1-3,5-6,8-9,11H2,(H,21,25)/t13-,14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP4 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50326381 (2S)-1-({(2S,4S)-4-[2-(6,7-Dihydrothieno[3,2-c]pyri...) Show SMILES O=C(C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N)N1CCc2ccsc2C1 |r| Show InChI InChI=1S/C19H22N4O3S/c20-10-14-2-1-5-23(14)19(26)15-8-13(18(25)21-15)9-17(24)22-6-3-12-4-7-27-16(12)11-22/h4,7,13-15H,1-3,5-6,8-9,11H2,(H,21,25)/t13-,14-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP2 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50326381 (2S)-1-({(2S,4S)-4-[2-(6,7-Dihydrothieno[3,2-c]pyri...) Show SMILES O=C(C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N)N1CCc2ccsc2C1 |r| Show InChI InChI=1S/C19H22N4O3S/c20-10-14-2-1-5-23(14)19(26)15-8-13(18(25)21-15)9-17(24)22-6-3-12-4-7-27-16(12)11-22/h4,7,13-15H,1-3,5-6,8-9,11H2,(H,21,25)/t13-,14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP9 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair