BDBM50326395 (2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl}pyrrolidine-2-boronic Acid::CHEMBL1243184

SMILES: OB(O)[C@@H]1CCCN1C(=O)[C@@H]1C[C@@H](CC(=O)N2Cc3ccccc3C2)C(=O)N1

InChI Key: InChIKey=ITLZQNVDXDVBBF-JYJNAYRXSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast activation protein alpha (Homo sapiens (Human))	BDBM50326395 ((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...) Show SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1C[C@@H](CC(=O)N2Cc3ccccc3C2)C(=O)N1 |r| Show InChI InChI=1S/C19H24BN3O5/c24-17(22-10-12-4-1-2-5-13(12)11-22)9-14-8-15(21-18(14)25)19(26)23-7-3-6-16(23)20(27)28/h1-2,4-5,14-16,27-28H,3,6-11H2,(H,21,25)/t14-,15-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant FAP expressed in Hi5 insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50326395 ((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...) Show SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1C[C@@H](CC(=O)N2Cc3ccccc3C2)C(=O)N1 |r| Show InChI InChI=1S/C19H24BN3O5/c24-17(22-10-12-4-1-2-5-13(12)11-22)9-14-8-15(21-18(14)25)19(26)23-7-3-6-16(23)20(27)28/h1-2,4-5,14-16,27-28H,3,6-11H2,(H,21,25)/t14-,15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP8 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50326395 ((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...) Show SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1C[C@@H](CC(=O)N2Cc3ccccc3C2)C(=O)N1 |r| Show InChI InChI=1S/C19H24BN3O5/c24-17(22-10-12-4-1-2-5-13(12)11-22)9-14-8-15(21-18(14)25)19(26)23-7-3-6-16(23)20(27)28/h1-2,4-5,14-16,27-28H,3,6-11H2,(H,21,25)/t14-,15-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP4 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50326395 ((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...) Show SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1C[C@@H](CC(=O)N2Cc3ccccc3C2)C(=O)N1 |r| Show InChI InChI=1S/C19H24BN3O5/c24-17(22-10-12-4-1-2-5-13(12)11-22)9-14-8-15(21-18(14)25)19(26)23-7-3-6-16(23)20(27)28/h1-2,4-5,14-16,27-28H,3,6-11H2,(H,21,25)/t14-,15-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP2 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50326395 ((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...) Show SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1C[C@@H](CC(=O)N2Cc3ccccc3C2)C(=O)N1 |r| Show InChI InChI=1S/C19H24BN3O5/c24-17(22-10-12-4-1-2-5-13(12)11-22)9-14-8-15(21-18(14)25)19(26)23-7-3-6-16(23)20(27)28/h1-2,4-5,14-16,27-28H,3,6-11H2,(H,21,25)/t14-,15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP9 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair