BDBM50327102 4'-Butoxy-2,6-difluoro-3'-{[2-fluoro-4-(trifluoromethyl)phenylamido]methyl}biphenyl-3-carboxylic acid::CHEMBL1254672

SMILES: CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1c(F)ccc(C(O)=O)c1F

InChI Key: InChIKey=FJLHBOXYGKPKMI-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50327102 (4'-Butoxy-2,6-difluoro-3'-{[2-fluoro-4-(trifluorom...) Show SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1c(F)ccc(C(O)=O)c1F Show InChI InChI=1S/C26H21F6NO4/c1-2-3-10-37-21-9-4-14(22-19(27)8-7-18(23(22)29)25(35)36)11-15(21)13-33-24(34)17-6-5-16(12-20(17)28)26(30,31)32/h4-9,11-12H,2-3,10,13H2,1H3,(H,33,34)(H,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at PPARdelta				J Med Chem 54: 1539-54 (2011) Article DOI: 10.1021/jm101356p BindingDB Entry DOI: 10.7270/Q27S7P30
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50327102 (4'-Butoxy-2,6-difluoro-3'-{[2-fluoro-4-(trifluorom...) Show SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1c(F)ccc(C(O)=O)c1F Show InChI InChI=1S/C26H21F6NO4/c1-2-3-10-37-21-9-4-14(22-19(27)8-7-18(23(22)29)25(35)36)11-15(21)13-33-24(34)17-6-5-16(12-20(17)28)26(30,31)32/h4-9,11-12H,2-3,10,13H2,1H3,(H,33,34)(H,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
					More data for this Ligand-Target Pair