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SMILES: Cc1ccc(cc1C(=O)N(CCCN)C1CCCCC1)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C

InChI Key: InChIKey=KZNDGYUJQVSRNW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327185   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50327185
PNG
(CHEMBL1256034 | N-(3-aminopropyl)-5-(3-tert-butyl-...)
Show SMILES Cc1ccc(cc1C(=O)N(CCCN)C1CCCCC1)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C
Show InChI InChI=1S/C35H44N6O2/c1-24-18-19-27(22-29(24)33(42)40(21-11-20-36)26-14-6-5-7-15-26)41-32(23-31(39-41)35(2,3)4)38-34(43)37-30-17-10-13-25-12-8-9-16-28(25)30/h8-10,12-13,16-19,22-23,26H,5-7,11,14-15,20-21,36H2,1-4H3,(H2,37,38,43)
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PubMed
 89n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to full-length GST-tagged p38alpha after 2.5 hrs by TR-FRET competition binding assay

Bioorg Med Chem Lett 20: 5787-92 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.097
BindingDB Entry DOI: 10.7270/Q2MC907J
More data for this
Ligand-Target Pair