BDBM50328008 3-[(1-Methyl-2(S)-azetidinyl)methoxy]-5-(piperidinyl)pyridineHydrochloride::CHEMBL1258465

SMILES: CN1CC[C@H]1COc1cncc(c1)N1CCCCC1

InChI Key: InChIKey=HIUXFELNILMSFU-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50328008 (3-[(1-Methyl-2(S)-azetidinyl)methoxy]-5-(piperidin...) Show SMILES CN1CC[C@H]1COc1cncc(c1)N1CCCCC1 |r| Show InChI InChI=1S/C15H23N3O/c1-17-8-5-13(17)12-19-15-9-14(10-16-11-15)18-6-3-2-4-7-18/h9-11,13H,2-8,12H2,1H3/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inactivation of nAChR alpha4beta2 in human SH-EP1 cells				J Med Chem 53: 6973-85 (2010) Article DOI: 10.1021/jm100765u BindingDB Entry DOI: 10.7270/Q25B03RQ
					More data for this Ligand-Target Pair