BDBM50328153 CHEMBL1257424::N-(2-morpholinoethyl)-3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide

SMILES: FC(F)(F)Oc1ccc(Nc2cc(ncn2)-c2cccc(c2)C(=O)NCCN2CCOCC2)cc1

InChI Key: InChIKey=QXCNFNHXEAQNBV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcr-Abl (Homo sapiens (Human))	BDBM50328153 (CHEMBL1257424 | N-(2-morpholinoethyl)-3-(6-(4-(tri...) Show SMILES FC(F)(F)Oc1ccc(Nc2cc(ncn2)-c2cccc(c2)C(=O)NCCN2CCOCC2)cc1 Show InChI InChI=1S/C24H24F3N5O3/c25-24(26,27)35-20-6-4-19(5-7-20)31-22-15-21(29-16-30-22)17-2-1-3-18(14-17)23(33)28-8-9-32-10-12-34-13-11-32/h1-7,14-16H,8-13H2,(H,28,33)(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of Bcr-Abl in mouse BA/F3 cells				J Med Chem 53: 6934-46 (2010) Article DOI: 10.1021/jm100555f BindingDB Entry DOI: 10.7270/Q2DJ5FTW
					More data for this Ligand-Target Pair