BDBM50328268 5-(2-chlorophenyl)-7-nitro-3-(pyridin-3-yl)-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine::CHEMBL1257434

SMILES: [O-][N+](=O)c1ccc2Nc3[nH]nc(c3N=C(c3ccccc3Cl)c2c1)-c1cccnc1

InChI Key: InChIKey=DOLVPPZXPDLQMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/Cyclin E/G1/S-specific cyclin E2 (Homo sapiens (Human))	BDBM50328268 (5-(2-chlorophenyl)-7-nitro-3-(pyridin-3-yl)-2,10-d...) Show SMILES [O-][N+](=O)c1ccc2Nc3[nH]nc(c3N=C(c3ccccc3Cl)c2c1)-c1cccnc1 |t:14| Show InChI InChI=1S/C21H13ClN6O2/c22-16-6-2-1-5-14(16)19-15-10-13(28(29)30)7-8-17(15)24-21-20(25-19)18(26-27-21)12-4-3-9-23-11-12/h1-11H,(H2,24,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2-cyclin E				Bioorg Med Chem Lett 20: 5984-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.079 BindingDB Entry DOI: 10.7270/Q21C1X42
					More data for this Ligand-Target Pair