BDBM50329169 (R)-N-benzyl-N-((3'-methyl-2',5'-dioxo-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-3-yl)methyl)pivalamide::CHEMBL1270087
SMILES: CN1C(=O)NC(=O)[C@]11Cc2cc3cc(CN(Cc4ccccc4)C(=O)C(C)(C)C)cnc3cc2C1
InChI Key: InChIKey=RVJHBDKIIZKJGU-MUUNZHRXSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM50329169 ((R)-N-benzyl-N-((3'-methyl-2',5'-dioxo-6,8-dihydro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co. Curated by ChEMBL | Assay Description Binding affinity to human recombinant CGRP receptor | Bioorg Med Chem Lett 20: 6827-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.105 BindingDB Entry DOI: 10.7270/Q2Z89CNJ | |||||||||||
More data for this Ligand-Target Pair |