BDBM50329635 CHEMBL1270443::tert-butyl 6-phenyl-9H-pyrido[3,4-b]indole-3-carboxylate

SMILES: CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccc(cc21)-c1ccccc1

InChI Key: InChIKey=OTWGFFXBGMUFBP-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50329635   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329635 (CHEMBL1270443 | tert-butyl 6-phenyl-9H-pyrido[3,4-...) Show SMILES CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccc(cc21)-c1ccccc1 Show InChI InChI=1S/C22H20N2O2/c1-22(2,3)26-21(25)19-12-17-16-11-15(14-7-5-4-6-8-14)9-10-18(16)24-20(17)13-23-19/h4-13,24H,1-3H3	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha2beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329635 (CHEMBL1270443 | tert-butyl 6-phenyl-9H-pyrido[3,4-...) Show SMILES CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccc(cc21)-c1ccccc1 Show InChI InChI=1S/C22H20N2O2/c1-22(2,3)26-21(25)19-12-17-16-11-15(14-7-5-4-6-8-14)9-10-18(16)24-20(17)13-23-19/h4-13,24H,1-3H3	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha1beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329635 (CHEMBL1270443 | tert-butyl 6-phenyl-9H-pyrido[3,4-...) Show SMILES CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccc(cc21)-c1ccccc1 Show InChI InChI=1S/C22H20N2O2/c1-22(2,3)26-21(25)19-12-17-16-11-15(14-7-5-4-6-8-14)9-10-18(16)24-20(17)13-23-19/h4-13,24H,1-3H3	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha3beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329635 (CHEMBL1270443 | tert-butyl 6-phenyl-9H-pyrido[3,4-...) Show SMILES CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccc(cc21)-c1ccccc1 Show InChI InChI=1S/C22H20N2O2/c1-22(2,3)26-21(25)19-12-17-16-11-15(14-7-5-4-6-8-14)9-10-18(16)24-20(17)13-23-19/h4-13,24H,1-3H3	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha5beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair
GABA receptor alpha-6/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329635 (CHEMBL1270443 | tert-butyl 6-phenyl-9H-pyrido[3,4-...) Show SMILES CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccc(cc21)-c1ccccc1 Show InChI InChI=1S/C22H20N2O2/c1-22(2,3)26-21(25)19-12-17-16-11-15(14-7-5-4-6-8-14)9-10-18(16)24-20(17)13-23-19/h4-13,24H,1-3H3	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha6beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair