BDBM50331034 2-phenyl-N-(1-(pyridin-2-yl)propyl)quinoline-4-carboxamide::CHEMBL1277892

SMILES: CCC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccn1

InChI Key: InChIKey=ZUKHCFDOVYFUHP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50331034 (2-phenyl-N-(1-(pyridin-2-yl)propyl)quinoline-4-car...) Show SMILES CCC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccn1 Show InChI InChI=1S/C24H21N3O/c1-2-20(22-14-8-9-15-25-22)27-24(28)19-16-23(17-10-4-3-5-11-17)26-21-13-7-6-12-18(19)21/h3-16,20H,2H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern Ohio Universities Colleges of Medicine and Pharmacy Curated by ChEMBL					Assay Description Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma counting				J Med Chem 53: 8080-8 (2010) Article DOI: 10.1021/jm1010012 BindingDB Entry DOI: 10.7270/Q2736R5F
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50331034 (2-phenyl-N-(1-(pyridin-2-yl)propyl)quinoline-4-car...) Show SMILES CCC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccn1 Show InChI InChI=1S/C24H21N3O/c1-2-20(22-14-8-9-15-25-22)27-24(28)19-16-23(17-10-4-3-5-11-17)26-21-13-7-6-12-18(19)21/h3-16,20H,2H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern Ohio Universities Colleges of Medicine and Pharmacy Curated by ChEMBL					Assay Description Antagonist activity against human NK3 receptor expressed in CHO cells assessed as inhibition of senktide-induced increase of intracellular calcium le...				J Med Chem 53: 8080-8 (2010) Article DOI: 10.1021/jm1010012 BindingDB Entry DOI: 10.7270/Q2736R5F
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50331034 (2-phenyl-N-(1-(pyridin-2-yl)propyl)quinoline-4-car...) Show SMILES CCC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccn1 Show InChI InChI=1S/C24H21N3O/c1-2-20(22-14-8-9-15-25-22)27-24(28)19-16-23(17-10-4-3-5-11-17)26-21-13-7-6-12-18(19)21/h3-16,20H,2H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern Ohio Universities Colleges of Medicine and Pharmacy Curated by ChEMBL					Assay Description Antagonist activity against human NK3 receptor expressed in HEK293 cells assessed as inhibition of MePhe7-NKB-induced increase of intracellular calci...				J Med Chem 53: 8080-8 (2010) Article DOI: 10.1021/jm1010012 BindingDB Entry DOI: 10.7270/Q2736R5F
					More data for this Ligand-Target Pair