BDBM50331430 1-{3-[(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-phenyl-amino]-propyl}-3-phenyl-urea::CHEMBL1290168

SMILES: O=C(NCCCN(C1=NS(=O)(=O)c2ccccc12)c1ccccc1)Nc1ccccc1

InChI Key: InChIKey=ZWPFGVJPFFFUJB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50331430 (1-{3-[(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...) Show SMILES O=C(NCCCN(C1=NS(=O)(=O)c2ccccc12)c1ccccc1)Nc1ccccc1 |t:7| Show InChI InChI=1S/C23H22N4O3S/c28-23(25-18-10-3-1-4-11-18)24-16-9-17-27(19-12-5-2-6-13-19)22-20-14-7-8-15-21(20)31(29,30)26-22/h1-8,10-15H,9,16-17H2,(H2,24,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of human voltage-gated potassium channel Kv1.3 expressed in CGE22 cells by patch clamp assay				Bioorg Med Chem Lett 20: 6983-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.132 BindingDB Entry DOI: 10.7270/Q2N58MMS
					More data for this Ligand-Target Pair