Found 5 hits for monomerid = 50332079 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM50332079
(2-(4-methoxyphenyl)-N-(2-(5-(trifluoromethyl)-1H-1...)Show SMILES COc1ccc(CC(=O)Nc2ccsc2-c2nnc([nH]2)C(F)(F)F)cc1 Show InChI InChI=1S/C16H13F3N4O2S/c1-25-10-4-2-9(3-5-10)8-12(24)20-11-6-7-26-13(11)14-21-15(23-22-14)16(17,18)19/h2-7H,8H2,1H3,(H,20,24)(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 20: 7303-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.066
BindingDB Entry DOI: 10.7270/Q20865JW |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM50332079
(2-(4-methoxyphenyl)-N-(2-(5-(trifluoromethyl)-1H-1...)Show SMILES COc1ccc(CC(=O)Nc2ccsc2-c2nnc([nH]2)C(F)(F)F)cc1 Show InChI InChI=1S/C16H13F3N4O2S/c1-25-10-4-2-9(3-5-10)8-12(24)20-11-6-7-26-13(11)14-21-15(23-22-14)16(17,18)19/h2-7H,8H2,1H3,(H,20,24)(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 20: 7303-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.066
BindingDB Entry DOI: 10.7270/Q20865JW |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50332079
(2-(4-methoxyphenyl)-N-(2-(5-(trifluoromethyl)-1H-1...)Show SMILES COc1ccc(CC(=O)Nc2ccsc2-c2nnc([nH]2)C(F)(F)F)cc1 Show InChI InChI=1S/C16H13F3N4O2S/c1-25-10-4-2-9(3-5-10)8-12(24)20-11-6-7-26-13(11)14-21-15(23-22-14)16(17,18)19/h2-7H,8H2,1H3,(H,20,24)(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of recombinant p38alpha after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 20: 7303-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.066
BindingDB Entry DOI: 10.7270/Q20865JW |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50332079
(2-(4-methoxyphenyl)-N-(2-(5-(trifluoromethyl)-1H-1...)Show SMILES COc1ccc(CC(=O)Nc2ccsc2-c2nnc([nH]2)C(F)(F)F)cc1 Show InChI InChI=1S/C16H13F3N4O2S/c1-25-10-4-2-9(3-5-10)8-12(24)20-11-6-7-26-13(11)14-21-15(23-22-14)16(17,18)19/h2-7H,8H2,1H3,(H,20,24)(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of recombinant Erk2 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 20: 7303-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.066
BindingDB Entry DOI: 10.7270/Q20865JW |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50332079
(2-(4-methoxyphenyl)-N-(2-(5-(trifluoromethyl)-1H-1...)Show SMILES COc1ccc(CC(=O)Nc2ccsc2-c2nnc([nH]2)C(F)(F)F)cc1 Show InChI InChI=1S/C16H13F3N4O2S/c1-25-10-4-2-9(3-5-10)8-12(24)20-11-6-7-26-13(11)14-21-15(23-22-14)16(17,18)19/h2-7H,8H2,1H3,(H,20,24)(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 20: 7303-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.066
BindingDB Entry DOI: 10.7270/Q20865JW |
More data for this
Ligand-Target Pair | |
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