BDBM50332464 2-(2-methyl-4-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methylselanyl)phenoxy)butanoic acid::CHEMBL1630381

SMILES: CCC(Oc1ccc([Se]Cc2sc(nc2C)-c2ccc(cc2)C(F)(F)F)cc1C)C(O)=O

InChI Key: InChIKey=YMULMPRRAPDSFG-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50332464 (2-(2-methyl-4-((4-methyl-2-(4-(trifluoromethyl)phe...) Show SMILES CCC(Oc1ccc([Se]Cc2sc(nc2C)-c2ccc(cc2)C(F)(F)F)cc1C)C(O)=O Show InChI InChI=1S/C23H22F3NO3SSe/c1-4-18(22(28)29)30-19-10-9-17(11-13(19)2)32-12-20-14(3)27-21(31-20)15-5-7-16(8-6-15)23(24,25)26/h5-11,18H,4,12H2,1-3H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	83.1	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 7239-42 (2010) Article DOI: 10.1016/j.bmcl.2010.10.103 BindingDB Entry DOI: 10.7270/Q2SN0975
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50332464 (2-(2-methyl-4-((4-methyl-2-(4-(trifluoromethyl)phe...) Show SMILES CCC(Oc1ccc([Se]Cc2sc(nc2C)-c2ccc(cc2)C(F)(F)F)cc1C)C(O)=O Show InChI InChI=1S/C23H22F3NO3SSe/c1-4-18(22(28)29)30-19-10-9-17(11-13(19)2)32-12-20-14(3)27-21(31-20)15-5-7-16(8-6-15)23(24,25)26/h5-11,18H,4,12H2,1-3H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPAR-gamma expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 7239-42 (2010) Article DOI: 10.1016/j.bmcl.2010.10.103 BindingDB Entry DOI: 10.7270/Q2SN0975
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50332464 (2-(2-methyl-4-((4-methyl-2-(4-(trifluoromethyl)phe...) Show SMILES CCC(Oc1ccc([Se]Cc2sc(nc2C)-c2ccc(cc2)C(F)(F)F)cc1C)C(O)=O Show InChI InChI=1S/C23H22F3NO3SSe/c1-4-18(22(28)29)30-19-10-9-17(11-13(19)2)32-12-20-14(3)27-21(31-20)15-5-7-16(8-6-15)23(24,25)26/h5-11,18H,4,12H2,1-3H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.20	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 7239-42 (2010) Article DOI: 10.1016/j.bmcl.2010.10.103 BindingDB Entry DOI: 10.7270/Q2SN0975
					More data for this Ligand-Target Pair