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SMILES: Cc1ccc(cc1)-c1nnc(Nc2ccc(Oc3ncccc3-c3cn[nH]c3N)cc2)c2ccccc12

InChI Key: InChIKey=IARKBTSLUXXRLP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333658   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50333658
PNG
(CHEMBL1643139 | N-(4-(3-(3-amino-1H-pyrazol-4-yl)p...)
Show SMILES Cc1ccc(cc1)-c1nnc(Nc2ccc(Oc3ncccc3-c3cn[nH]c3N)cc2)c2ccccc12
Show InChI InChI=1S/C29H23N7O/c1-18-8-10-19(11-9-18)26-22-5-2-3-6-23(22)28(36-34-26)33-20-12-14-21(15-13-20)37-29-24(7-4-16-31-29)25-17-32-35-27(25)30/h2-17H,1H3,(H,33,36)(H3,30,32,35)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged Aurora A kinase expressed in insect cells

Bioorg Med Chem 19: 907-16 (2011)


Article DOI: 10.1016/j.bmc.2010.11.064
BindingDB Entry DOI: 10.7270/Q2V40VGC
More data for this
Ligand-Target Pair