BDBM50333960 CHEMBL1644477::exo-(1R,5S)-3-(3-iodophenoxy)-8-azabicyclo[3.2.1]octane

SMILES: Ic1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3)c1

InChI Key: InChIKey=LXIOTZOSBNBEKN-PTEHBNRSSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50333960 (CHEMBL1644477 | exo-(1R,5S)-3-(3-iodophenoxy)-8-az...) Show SMILES Ic1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3)c1 |r| Show InChI InChI=1S/C13H16INO/c14-9-2-1-3-12(6-9)16-13-7-10-4-5-11(8-13)15-10/h1-3,6,10-11,13,15H,4-5,7-8H2/t10-,11+,13-	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation counting				Bioorg Med Chem Lett 21: 271-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50333960 (CHEMBL1644477 | exo-(1R,5S)-3-(3-iodophenoxy)-8-az...) Show SMILES Ic1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3)c1 |r| Show InChI InChI=1S/C13H16INO/c14-9-2-1-3-12(6-9)16-13-7-10-4-5-11(8-13)15-10/h1-3,6,10-11,13,15H,4-5,7-8H2/t10-,11+,13-	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	804	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation counting				Bioorg Med Chem Lett 21: 271-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50333960 (CHEMBL1644477 | exo-(1R,5S)-3-(3-iodophenoxy)-8-az...) Show SMILES Ic1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3)c1 |r| Show InChI InChI=1S/C13H16INO/c14-9-2-1-3-12(6-9)16-13-7-10-4-5-11(8-13)15-10/h1-3,6,10-11,13,15H,4-5,7-8H2/t10-,11+,13-	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation counting				Bioorg Med Chem Lett 21: 271-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3
					More data for this Ligand-Target Pair