BindingDB logo
myBDB logout

null

SMILES: Cc1cc(CN2Cc3ccccc3C2C(=O)Nc2ccc(Cl)cc2)ccc1OCC(O)=O

InChI Key: InChIKey=HEIDRJCIGVPEET-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334838   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50334838
PNG
(2-(4-((1-(4-chlorophenylcarbamoyl)isoindolin-2-yl)...)
Show SMILES Cc1cc(CN2Cc3ccccc3C2C(=O)Nc2ccc(Cl)cc2)ccc1OCC(O)=O
Show InChI InChI=1S/C25H23ClN2O4/c1-16-12-17(6-11-22(16)32-15-23(29)30)13-28-14-18-4-2-3-5-21(18)24(28)25(31)27-20-9-7-19(26)8-10-20/h2-12,24H,13-15H2,1H3,(H,27,31)(H,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 2.50E+3n/an/an/an/a



AstraZeneca R&D Charnwood

Curated by ChEMBL


Assay Description
Agonist activity at GAL4-fused human PPARdelta DNA binding domain expressed in HEK293 cells by luciferase reporter gene assay

Bioorg Med Chem Lett 21: 492-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.10.117
BindingDB Entry DOI: 10.7270/Q2ST7Q3Q
More data for this
Ligand-Target Pair