BDBM50335496 4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfonate::CHEMBL1651846

SMILES: CS(=O)(=O)Oc1ccc(cc1)S(=O)(=O)CC1CS1

InChI Key: InChIKey=LWHDLJDNHJFUSI-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50335496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335496 (4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...) Show SMILES CS(=O)(=O)Oc1ccc(cc1)S(=O)(=O)CC1CS1 Show InChI InChI=1S/C10H12O5S3/c1-17(11,12)15-8-2-4-10(5-3-8)18(13,14)7-9-6-16-9/h2-5,9H,6-7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometry				ACS Med Chem Lett 2: 177-181 (2011) Article DOI: 10.1021/ml100254e BindingDB Entry DOI: 10.7270/Q2N29X6G
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14) (Homo sapiens (Human))	BDBM50335496 (4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...) Show SMILES CS(=O)(=O)Oc1ccc(cc1)S(=O)(=O)CC1CS1 Show InChI InChI=1S/C10H12O5S3/c1-17(11,12)15-8-2-4-10(5-3-8)18(13,14)7-9-6-16-9/h2-5,9H,6-7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometry				ACS Med Chem Lett 2: 177-181 (2011) Article DOI: 10.1021/ml100254e BindingDB Entry DOI: 10.7270/Q2N29X6G
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50335496 (4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...) Show SMILES CS(=O)(=O)Oc1ccc(cc1)S(=O)(=O)CC1CS1 Show InChI InChI=1S/C10H12O5S3/c1-17(11,12)15-8-2-4-10(5-3-8)18(13,14)7-9-6-16-9/h2-5,9H,6-7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometry				ACS Med Chem Lett 2: 177-181 (2011) Article DOI: 10.1021/ml100254e BindingDB Entry DOI: 10.7270/Q2N29X6G
					More data for this Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human))	BDBM50335496 (4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...) Show SMILES CS(=O)(=O)Oc1ccc(cc1)S(=O)(=O)CC1CS1 Show InChI InChI=1S/C10H12O5S3/c1-17(11,12)15-8-2-4-10(5-3-8)18(13,14)7-9-6-16-9/h2-5,9H,6-7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometry				ACS Med Chem Lett 2: 177-181 (2011) Article DOI: 10.1021/ml100254e BindingDB Entry DOI: 10.7270/Q2N29X6G
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50335496 (4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...) Show SMILES CS(=O)(=O)Oc1ccc(cc1)S(=O)(=O)CC1CS1 Show InChI InChI=1S/C10H12O5S3/c1-17(11,12)15-8-2-4-10(5-3-8)18(13,14)7-9-6-16-9/h2-5,9H,6-7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP1 catalytic domain by substrate hydrolysis based fluorescence spectrophotometry				ACS Med Chem Lett 2: 177-181 (2011) Article DOI: 10.1021/ml100254e BindingDB Entry DOI: 10.7270/Q2N29X6G
					More data for this Ligand-Target Pair