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SMILES: CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31

InChI Key: InChIKey=SWSVYEJPIAYSGL-GOSISDBHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50336861 (CHEMBL1672310 | N-propyl-2-fluoroethoxy-11-monohyd...) Show SMILES CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 |r| Show InChI InChI=1S/C21H24FNO2/c1-2-8-23-9-6-15-11-16(25-10-7-22)13-17-20(15)18(23)12-14-4-3-5-19(24)21(14)17/h3-5,11,13,18,24H,2,6-10,12H2,1H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]domperidone from dopamine D2 receptor high binding site in Sprague-Dawley rat striatum by scintillation counting				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50336861 (CHEMBL1672310 | N-propyl-2-fluoroethoxy-11-monohyd...) Show SMILES CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 |r| Show InChI InChI=1S/C21H24FNO2/c1-2-8-23-9-6-15-11-16(25-10-7-22)13-17-20(15)18(23)12-14-4-3-5-19(24)21(14)17/h3-5,11,13,18,24H,2,6-10,12H2,1H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D2 receptor low binding site in Sprague-Dawley rat striatum by scintillation counting				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50336861 (CHEMBL1672310 | N-propyl-2-fluoroethoxy-11-monohyd...) Show SMILES CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 |r| Show InChI InChI=1S/C21H24FNO2/c1-2-8-23-9-6-15-11-16(25-10-7-22)13-17-20(15)18(23)12-14-4-3-5-19(24)21(14)17/h3-5,11,13,18,24H,2,6-10,12H2,1H3/t18-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]domperidone from rat cloned dopamine D3 receptor				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50336861 (CHEMBL1672310 | N-propyl-2-fluoroethoxy-11-monohyd...) Show SMILES CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 |r| Show InChI InChI=1S/C21H24FNO2/c1-2-8-23-9-6-15-11-16(25-10-7-22)13-17-20(15)18(23)12-14-4-3-5-19(24)21(14)17/h3-5,11,13,18,24H,2,6-10,12H2,1H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor low binding site by radioligand displacement assay				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
					More data for this Ligand-Target Pair