BDBM50337157 7-methyl-2-(4-(2-oxo-3-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)propyl)phenyl)benzo[d]oxazole-5-carbonitrile::CHEMBL1682752

SMILES: Cc1cc(cc2nc(oc12)-c1ccc(CC(=O)CN2CCN(CC2)c2ccc(cc2)C(F)(F)F)cc1)C#N

InChI Key: InChIKey=XYFKIUYEPWNNKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50337157 (7-methyl-2-(4-(2-oxo-3-(4-(4-(trifluoromethyl)phen...) Show SMILES Cc1cc(cc2nc(oc12)-c1ccc(CC(=O)CN2CCN(CC2)c2ccc(cc2)C(F)(F)F)cc1)C#N Show InChI InChI=1S/C29H25F3N4O2/c1-19-14-21(17-33)16-26-27(19)38-28(34-26)22-4-2-20(3-5-22)15-25(37)18-35-10-12-36(13-11-35)24-8-6-23(7-9-24)29(30,31)32/h2-9,14,16H,10-13,15,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CETP				Bioorg Med Chem Lett 21: 1890-5 (2011) Article DOI: 10.1016/j.bmcl.2010.11.090 BindingDB Entry DOI: 10.7270/Q2NG4QW6
					More data for this Ligand-Target Pair