BDBM50338252 7-(2-methoxyethyl)-2-ureido-5,7-dihydro-4H-thieno[2,3-e]indazole-3-carboxamide::CHEMBL1681976

SMILES: COCCn1cc-2c(CCc3c-2sc(NC(N)=O)c3C(N)=O)n1

InChI Key: InChIKey=YJJNBANRZSLOOR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338252   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50338252 (7-(2-methoxyethyl)-2-ureido-5,7-dihydro-4H-thieno[...) Show SMILES COCCn1cc-2c(CCc3c-2sc(NC(N)=O)c3C(N)=O)n1 Show InChI InChI=1S/C14H17N5O3S/c1-22-5-4-19-6-8-9(18-19)3-2-7-10(12(15)20)13(17-14(16)21)23-11(7)8/h6H,2-5H2,1H3,(H2,15,20)(H3,16,17,21)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human IKK-beta by substrate phosphorylation assay				Bioorg Med Chem Lett 21: 1758-62 (2011) Article DOI: 10.1016/j.bmcl.2011.01.069 BindingDB Entry DOI: 10.7270/Q2TX3FPV
					More data for this Ligand-Target Pair