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SMILES: COc1cccc(OCc2nc3c(OC)cc(cc3c(=O)[nH]2)-c2cn[nH]c2)c1

InChI Key: InChIKey=UYTMCHWFMUYGJQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338722   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))		BDBM50338722
PNG
(8-methoxy-2-((3-methoxyphenoxy)methyl)-6-(1H-pyraz...)
Show SMILES COc1cccc(OCc2nc3c(OC)cc(cc3c(=O)[nH]2)-c2cn[nH]c2)c1
Show InChI InChI=1S/C20H18N4O4/c1-26-14-4-3-5-15(8-14)28-11-18-23-19-16(20(25)24-18)6-12(7-17(19)27-2)13-9-21-22-10-13/h3-10H,11H2,1-2H3,(H,21,22)(H,23,24,25)
PDB
MMDB

KEGG

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PC sid
UniChem

Similars
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Translational Research Institute

Curated by ChEMBL


Assay Description
Inhibition of ROCK2 by HTRF assay

Bioorg Med Chem Lett 21: 1844-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.039
BindingDB Entry DOI: 10.7270/Q20G3KFF
More data for this
Ligand-Target Pair