BDBM50339107 5-(aminomethyl)-N-(3,4-dichlorobenzyl)-4-(4-methoxyphenyl)-6-methylpicolinamide::CHEMBL1688435

SMILES: COc1ccc(cc1)-c1cc(nc(C)c1CN)C(=O)NCc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=GWTAEZPFUNDLNK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50339107 (5-(aminomethyl)-N-(3,4-dichlorobenzyl)-4-(4-methox...) Show SMILES COc1ccc(cc1)-c1cc(nc(C)c1CN)C(=O)NCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H21Cl2N3O2/c1-13-18(11-25)17(15-4-6-16(29-2)7-5-15)10-21(27-13)22(28)26-12-14-3-8-19(23)20(24)9-14/h3-10H,11-12,25H2,1-2H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...				ACS Med Chem Lett 1: 530-535 (2010) Article DOI: 10.1021/ml100200c BindingDB Entry DOI: 10.7270/Q2513ZGH
					More data for this Ligand-Target Pair