BDBM50339477 3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]-2-methylphenyl}propanoic Acid::CHEMBL1688474
SMILES: Cc1cc(OCc2cccc(c2)-c2c(C)cccc2C)ccc1CCC(O)=O
InChI Key: InChIKey=MXTQGUYGYRXCBC-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50339477 (3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]-2-meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Agonist activity against human GPR40 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPR assay in presence of 0.1% BS... | J Med Chem 54: 1365-78 (2011) Article DOI: 10.1021/jm101405t BindingDB Entry DOI: 10.7270/Q2251JG7 | |||||||||||
More data for this Ligand-Target Pair |