BDBM50340322 (R)-1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-yl)ethyl)imidazo[1,5-a]pyrazine-3-carboxamide::CHEMBL1760942

SMILES: FC(F)(F)[C@H](NC(=O)c1nc(N2CCOCC2)c2cnccn12)c1ccccn1

InChI Key: InChIKey=QHPGFWKRMZAINM-CQSZACIVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50340322 ((R)-1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-y...) Show SMILES FC(F)(F)[C@H](NC(=O)c1nc(N2CCOCC2)c2cnccn12)c1ccccn1 |r| Show InChI InChI=1S/C18H17F3N6O2/c19-18(20,21)14(12-3-1-2-4-23-12)24-17(28)16-25-15(26-7-9-29-10-8-26)13-11-22-5-6-27(13)16/h1-6,11,14H,7-10H2,(H,24,28)/t14-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 21: 2354-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.082 BindingDB Entry DOI: 10.7270/Q2C829MB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50340322 ((R)-1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-y...) Show SMILES FC(F)(F)[C@H](NC(=O)c1nc(N2CCOCC2)c2cnccn12)c1ccccn1 |r| Show InChI InChI=1S/C18H17F3N6O2/c19-18(20,21)14(12-3-1-2-4-23-12)24-17(28)16-25-15(26-7-9-29-10-8-26)13-11-22-5-6-27(13)16/h1-6,11,14H,7-10H2,(H,24,28)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 21: 2354-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.082 BindingDB Entry DOI: 10.7270/Q2C829MB
					More data for this Ligand-Target Pair