BDBM50341129 4-ethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(pyridin-3-yl)thiazol-2-ylamino)benzamide::CHEMBL1760375

SMILES: CCc1ccc(cc1Nc1nc(cs1)-c1cccnc1)C(=O)Nc1cc(cc(c1)C(F)(F)F)-n1cnc(C)c1

InChI Key: InChIKey=RCKUTXYPADMBLF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcr-Abl (Homo sapiens (Human))	BDBM50341129 (4-ethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(triflu...) Show SMILES CCc1ccc(cc1Nc1nc(cs1)-c1cccnc1)C(=O)Nc1cc(cc(c1)C(F)(F)F)-n1cnc(C)c1 Show InChI InChI=1S/C28H23F3N6OS/c1-3-18-6-7-19(9-24(18)35-27-36-25(15-39-27)20-5-4-8-32-13-20)26(38)34-22-10-21(28(29,30)31)11-23(12-22)37-14-17(2)33-16-37/h4-16H,3H2,1-2H3,(H,34,38)(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Bcr/Abl by FRET-based Z-lyte assay				Bioorg Med Chem Lett 21: 1965-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.029 BindingDB Entry DOI: 10.7270/Q26D5T9G
					More data for this Ligand-Target Pair