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SMILES: FC(F)(F)c1cccc(c1)-c1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1

InChI Key: InChIKey=CVTGJVKEEGMPND-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341485   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50341485 (8-{5-[3-(Trifluoromethyl)phenyl]pyridin-3-yl}-1,2,...) Show SMILES FC(F)(F)c1cccc(c1)-c1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1 Show InChI InChI=1S/C23H17F3N2O/c24-23(25,26)20-3-1-2-14(11-20)18-10-19(13-27-12-18)17-8-15-4-5-21(29)28-7-6-16(9-17)22(15)28/h1-3,8-13H,4-7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assay				J Med Chem 54: 2307-19 (2011) Article DOI: 10.1021/jm101470k BindingDB Entry DOI: 10.7270/Q2765FM6
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50341485 (8-{5-[3-(Trifluoromethyl)phenyl]pyridin-3-yl}-1,2,...) Show SMILES FC(F)(F)c1cccc(c1)-c1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1 Show InChI InChI=1S/C23H17F3N2O/c24-23(25,26)20-3-1-2-14(11-20)18-10-19(13-27-12-18)17-8-15-4-5-21(29)28-7-6-16(9-17)22(15)28/h1-3,8-13H,4-7H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assay				J Med Chem 54: 2307-19 (2011) Article DOI: 10.1021/jm101470k BindingDB Entry DOI: 10.7270/Q2765FM6
					More data for this Ligand-Target Pair