BDBM50342688 1-(5-methylpyridin-2-yl)-1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidine::CHEMBL1771090

SMILES: Cc1ccc(nc1)N1CCC(CC1)C1CCN(CC1)c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=RWXDSWAVXKMDMF-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50342688 (1-(5-methylpyridin-2-yl)-1'-(4-(methylsulfonyl)phe...) Show SMILES Cc1ccc(nc1)N1CCC(CC1)C1CCN(CC1)c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H31N3O2S/c1-18-3-8-23(24-17-18)26-15-11-20(12-16-26)19-9-13-25(14-10-19)21-4-6-22(7-5-21)29(2,27)28/h3-8,17,19-20H,9-16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...				Bioorg Med Chem Lett 21: 2665-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.086 BindingDB Entry DOI: 10.7270/Q2M61KJV
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50342688 (1-(5-methylpyridin-2-yl)-1'-(4-(methylsulfonyl)phe...) Show SMILES Cc1ccc(nc1)N1CCC(CC1)C1CCN(CC1)c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H31N3O2S/c1-18-3-8-23(24-17-18)26-15-11-20(12-16-26)19-9-13-25(14-10-19)21-4-6-22(7-5-21)29(2,27)28/h3-8,17,19-20H,9-16H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...				Bioorg Med Chem Lett 21: 2665-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.086 BindingDB Entry DOI: 10.7270/Q2M61KJV
					More data for this Ligand-Target Pair