null
SMILES: Cn1c(cc(=O)n(C)c1=O)N1CCN(CC\C=C2/c3ccccc3COc3ccc(CC(O)=O)cc23)CC1
InChI Key: InChIKey=NIKHLOHBEKSSNM-LIMNOBDPSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H1 receptor (Homo sapiens (Human)) | BDBM50343586 ((E)-2-(11-(3-(4-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-te...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co., Ltd Curated by ChEMBL | Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 3005-21 (2011) Article DOI: 10.1016/j.bmc.2011.03.003 BindingDB Entry DOI: 10.7270/Q23T9HJM | |||||||||||
More data for this Ligand-Target Pair |