BDBM50344152 6-(3-isopropoxy-5-phenoxybenzamido)nicotinic acid::CHEMBL1778364

SMILES: CC(C)Oc1cc(Oc2ccccc2)cc(c1)C(=O)Nc1ccc(cn1)C(O)=O

InChI Key: InChIKey=MIIWULADOLVWHB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50344152 (6-(3-isopropoxy-5-phenoxybenzamido)nicotinic acid ...) Show SMILES CC(C)Oc1cc(Oc2ccccc2)cc(c1)C(=O)Nc1ccc(cn1)C(O)=O Show InChI InChI=1S/C22H20N2O5/c1-14(2)28-18-10-16(11-19(12-18)29-17-6-4-3-5-7-17)21(25)24-20-9-8-15(13-23-20)22(26)27/h3-14H,1-2H3,(H,26,27)(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by ChEMBL					Assay Description Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometrically				Bioorg Med Chem Lett 21: 3467-70 (2011) Article DOI: 10.1016/j.bmcl.2011.03.093 BindingDB Entry DOI: 10.7270/Q2Z038HG
					More data for this Ligand-Target Pair