BDBM50345102 2-(9-chloro-2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylthio)acetonitrile::CHEMBL1779383

SMILES: Cc1nc2c3cc(Cl)ccc3nc(SCC#N)n2n1

InChI Key: InChIKey=JVWVOSDINSVKSI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50345102 (2-(9-chloro-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...) Show SMILES Cc1nc2c3cc(Cl)ccc3nc(SCC#N)n2n1 Show InChI InChI=1S/C12H8ClN5S/c1-7-15-11-9-6-8(13)2-3-10(9)16-12(18(11)17-7)19-5-4-14/h2-3,6H,5H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Inhibition of PDE10A				Bioorg Med Chem Lett 21: 3738-42 (2011) Article DOI: 10.1016/j.bmcl.2011.04.067 BindingDB Entry DOI: 10.7270/Q24B31PT
					More data for this Ligand-Target Pair