BDBM50346252 7-(2-Fluoro-phenylsulfanyl)-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indole::CHEMBL1782363
SMILES: Fc1ccccc1Sc1ccc2CC3CNCCN3c2c1
InChI Key: InChIKey=FIZHFFJIUODSTI-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50346252 (7-(2-Fluoro-phenylsulfanyl)-1,2,3,4,10,10a-hexahyd...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor in human tsA201 cells | Bioorg Med Chem Lett 20: 5431-3 (2010) Article DOI: 10.1016/j.bmcl.2010.07.105 BindingDB Entry DOI: 10.7270/Q2RV0P1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50346252 (7-(2-Fluoro-phenylsulfanyl)-1,2,3,4,10,10a-hexahyd...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]5-LSD from human 5HT6 receptor expressed in human HeLa cells | Bioorg Med Chem Lett 20: 5431-3 (2010) Article DOI: 10.1016/j.bmcl.2010.07.105 BindingDB Entry DOI: 10.7270/Q2RV0P1S | |||||||||||
More data for this Ligand-Target Pair |