BDBM50346339 4-Methyl-3,6-di-O-methyl-alpha-mangostin::CHEMBL1782244
SMILES: [#6]-[#8]-c1cc2oc3c(-[#6])c(-[#8]-[#6])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c3c(=O)c2c(-[#6]\[#6]=[#6](\[#6])-[#6])c1-[#8]-[#6]
InChI Key: InChIKey=MABUETXAZCIAOZ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nuclear factor NF-kappa-B (Homo sapiens (Human)) | BDBM50346339 (4-Methyl-3,6-di-O-methyl-alpha-mangostin | CHEMBL1...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Ohio State University Curated by ChEMBL | Assay Description Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI... | J Nat Prod 74: 1117-25 (2011) Article DOI: 10.1021/np200051j BindingDB Entry DOI: 10.7270/Q20C4W31 | |||||||||||
More data for this Ligand-Target Pair |