BDBM50346376 3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)benzo[d][1,2,3]triazin-4(3H)-one::CHEMBL1783347

SMILES: O=c1n(CCCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12

InChI Key: InChIKey=VTPLXEUSMDJJMM-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50346376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50346376 (3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...) Show SMILES O=c1n(CCCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12 Show InChI InChI=1S/C24H25N5O/c30-24-21-10-3-4-11-22(21)25-26-29(24)14-6-13-27-15-17-28(18-16-27)23-12-5-8-19-7-1-2-9-20(19)23/h1-5,7-12H,6,13-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation counting				Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50346376 (3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...) Show SMILES O=c1n(CCCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12 Show InChI InChI=1S/C24H25N5O/c30-24-21-10-3-4-11-22(21)25-26-29(24)14-6-13-27-15-17-28(18-16-27)23-12-5-8-19-7-1-2-9-20(19)23/h1-5,7-12H,6,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 mins				Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50346376 (3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...) Show SMILES O=c1n(CCCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12 Show InChI InChI=1S/C24H25N5O/c30-24-21-10-3-4-11-22(21)25-26-29(24)14-6-13-27-15-17-28(18-16-27)23-12-5-8-19-7-1-2-9-20(19)23/h1-5,7-12H,6,13-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation counting				Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50346376 (3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...) Show SMILES O=c1n(CCCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12 Show InChI InChI=1S/C24H25N5O/c30-24-21-10-3-4-11-22(21)25-26-29(24)14-6-13-27-15-17-28(18-16-27)23-12-5-8-19-7-1-2-9-20(19)23/h1-5,7-12H,6,13-18H2	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat frontal cortical homogenates after 15 mins				Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50346376 (3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)ben...) Show SMILES O=c1n(CCCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12 Show InChI InChI=1S/C24H25N5O/c30-24-21-10-3-4-11-22(21)25-26-29(24)14-6-13-27-15-17-28(18-16-27)23-12-5-8-19-7-1-2-9-20(19)23/h1-5,7-12H,6,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation counting				Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J
					More data for this Ligand-Target Pair